Scintillation proximity radioimmunoassay with microporous membranes

Autor: Robert K. Mansfield, Neil G. Hartman, Dibakar Bhattacharyya, Michael Jay
Rok vydání: 1996
Předmět:
Zdroj: Applied Radiation and Isotopes. 47:323-328
ISSN: 0969-8043
DOI: 10.1016/0969-8043(95)00299-5
Popis: Fluors were incorporated into the matrix of microporous polymeric membranes and antibodies were subsequently bound to their surfaces. These membranes were used in competitive binding assays (secondary RIAs) for cyclic-AMP in which the bound and unbound radioligands did not require separation. Membrane-based scintillation proximity assay have utility for the detection of a variety of radioanalytes and can be configured in a number of sizes and shapes.
Databáze: OpenAIRE