Kuroshines A and B, new alkaloids from Zoanthus kuroshio

Autor: Wan Chun Lai, Yuan-Bin Cheng, Fang Rong Chang, Yu Chi Tsai, Chih Chin Lan, Wei Chun Liu, Yang Chang Wu, Michael Y. Chiang
Rok vydání: 2014
Předmět:
Zdroj: Tetrahedron Letters. 55:5369-5372
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2014.07.101
Popis: A chemical investigation of Zoanthus kuroshio has yielded two new alkaloids, kuroshines A (1) and B (2). The compounds possess a densely functionalized ring system on the basis of the zoanthamine frames. The structures of 1 and 2 were elucidated through interpretation of spectroscopic methods, especially 2D NMR techniques (COSY, HMQC, HMBC, and ROESY). The absolute stereochemistry of 1 was further confirmed by an X-ray single crystallographic analysis using a mirror Cu-Kα radiation.
Databáze: OpenAIRE