Details of the antioxidant mechanism of hydroxycinnamic acids
| Autor: | Bao-Yong Liu, Ya-Jing Shang, Meng-Meng Zhao |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Reaction mechanism
Antioxidant Hydrogen 010405 organic chemistry medicine.medical_treatment Ethyl acetate chemistry.chemical_element 010402 general chemistry 01 natural sciences Chemical reaction 0104 chemical sciences chemistry.chemical_compound Electron transfer chemistry medicine Molecule Organic chemistry Methanol Food Science |
| Zdroj: | Czech Journal of Food Sciences. 33:210-216 |
| ISSN: | 1805-9317 1212-1800 |
| DOI: | 10.17221/611/2014-cjfs |
| Popis: | Antioxidant activities and free radical-mediated DNA strand breakages of five hydroxycinnamic acids were examined. Kinetic analysis of a stable galvinoxy (GO•)-scavenging reaction of hydroxycinnamic acids demonstrated that the molecular structure and the reaction medium were two important factors affecting the antioxidant mechanism and activity. In methanol, the kinetic process of the compounds, which have electron-donating groups (-OH, -OCH 3 ) in the ortho - or para -position of 4-OH, was primarily governed by the sequential proton loss electron transfer (SPLET mechanism). While, in ethyl acetate, the reaction mechanism is predominantly direct hydrogen atom transfer (HAT mechanism). But for the compounds having only one hydroxyl, both in ethyl acetate and methanol, the reaction mechanism is only HAT. At the same time, the compound bearing o-diphenoxyl is not the most active one in our tested environment. |
| Databáze: | OpenAIRE |
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