Neonatal hyperbilirubinemia and bilirubin neurotoxicity in hospitalized neonates: analysis of the US Database
| Autor: | Mohamed A. Mohamed, Marwa M Elgendy, Ibrahim Qattea, Hany Aly, Mohsen A. A. Farghaly |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
education.field_of_study Pediatrics Bilirubin business.industry Population Odds ratio Jaundice medicine.disease Confidence interval Postnatal age chemistry.chemical_compound chemistry Pediatrics Perinatology and Child Health Pediatric surgery medicine Kernicterus medicine.symptom business education |
| Zdroj: | Pediatric Research. 91:1662-1668 |
| ISSN: | 1530-0447 0031-3998 |
| DOI: | 10.1038/s41390-021-01692-3 |
| Popis: | The objective of this study was to assess the prevalence and trends for neonatal hyperbilirubinemia, and the development of bilirubin neurotoxicity in the USA. We used a de-identified national dataset for the years 2002–2017. The study included all newborn inpatients with postnatal age ≤28 days. Cochran–Armitage trend test was used for trend analyses. Regression analyses were performed and adjusted odds ratios (aOR) were reported. The study included 57,989,476 infants; of them 53,259,758 (91.8%) were term infants and 4,725,178 (8.2%) were preterm infants. Bilirubin neurotoxicity decreased over the years in term infants (Z = 0.36, p = 0.03) without change in preterm infants (Z = 42.5, p = 0.12). Black neonates were less likely to be diagnosed with hyperbilirubinemia than White neonates (aOR = 0.77, 95% confidence interval (CI): 0.77–0.78, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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