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The techniques applied by mechanical engineers to problems of machinery condition monitoring can also be applied in other fields. This paper discusses applying techniques that are regularly applied to machinery and system condition monitoring to the human cardiovascular system. Techniques such as physics-based system modeling coupled with limited measurements can be used to infer the condition of a system or specific component. In this case, a mathematical model of the flow through the cardiovascular system was implemented and can be used independently to simulate system performance. Given basic system parameters including heart rate and vascular resistances, the model generates time varying flows and pressures in different portions of the system. The model can be used to interpret a measurement performed on the system to obtain additional information about the state of the system. In this case pulse waveform information is used to make a system flow measurement. This paper will provide an overview of the technique used, the structure of the model, and the initial validation with patient data. |
