PULMONARY MANIFESTATIONS OF GOODPASTURE'S SYNDROME
| Autor: | Joseph A. Ball, K. Randall Young |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Pulmonary and Respiratory Medicine
Basement membrane Pathology medicine.medical_specialty business.industry Renal glomerulus Respiratory disease Glomerulonephritis medicine.disease medicine.anatomical_structure Immunology medicine Goodpasture's syndrome Goodpasture syndrome Pulmonary hemorrhage business Kidney disease |
| Zdroj: | Clinics in Chest Medicine. 19:777-791 |
| ISSN: | 0272-5231 |
| Popis: | Goodpasture's syndrome, or antiglomerular basement membrane disease, is a disorder in which lungs and kidneys are affected by the binding of anti-GBM antibodies, leading to pulmonary hemorrhage and glomerulonephritis with rapidly progressive renal insufficiency. Recent advances in the understanding of disease pathogenesis and diagnosis and treatment have significantly improved our ability to recognize the syndrome, distinguish it from other similar disorders, and offer successful treatment. This article focuses on the pathogenetic features, clinical manifestations, diagnostic strategies, and therapeutic principles of anti-GBM disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|