Study of the Aniline and Acetone Condensation Reaction under Electrospray Ionization Conditions

Autor:	I. A. Gromov, O. V. Polyakova, Albert T. Lebedev, D. M. Mazur, D. O. Kuleshov, N. R. Gall, E. N. Alekseyuk, L. N. Gall
Rok vydání:	2020
Předmět:	Formic acid Electrospray ionization 010401 analytical chemistry Inorganic chemistry Condensation 010402 general chemistry Mass spectrometry Condensation reaction 01 natural sciences Chemical reaction 0104 chemical sciences Analytical Chemistry chemistry.chemical_compound Aniline chemistry Acetone
Zdroj:	Journal of Analytical Chemistry. 75:1647-1652
ISSN:	1608-3199 1061-9348
DOI:	10.1134/s1061934820130067
Popis:	The present paper deals with the study of condensation reaction of aniline with acetone under electrospray ionization (ESI) conditions . An experimental setup is described for conducting reactions under ESI conditions with a possibility of the accumulation of reaction products. The aniline and acetone condensation products were analyzed by gas chromatography–mass spectrometry. Spraying this mixture with high concentration of formic acid, results in the formation of N-phenylformamide, N,N'-diphenylmethaneimidamide, and 1,2-dihydro-2,2,4-trimethylquinoline; the last one is the only product of the reaction of aniline with acetone. Thus, the Schiff base formation reaction radically changes its direction. The results obtained using the proposed experimental setup open up new prospects both for studying chemical reactions in charged microdroplets and for the use of ESI as a preparative method for the synthesis of organic compounds.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::333bcc7d2d5a459f6a47f98e0da8e1b0 https://doi.org/10.1134/s1061934820130067 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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