Intra-articular formulation of colchicine loaded nanoemulsion systems for enhanced locoregional drug delivery: in vitro characterization, 99mTc coupling and in vivo biodistribution studies

Autor:	Mohamed H. Aboumanei, Hend Fayez
Rok vydání:	2021
Předmět:	Drug media_common.quotation_subject Pharmaceutical Science 02 engineering and technology Pharmacology 030226 pharmacology & pharmacy 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Therapeutic index Intra articular Drug Discovery Colchicine Medicine media_common business.industry Organic Chemistry 021001 nanoscience & nanotechnology In vitro chemistry In vivo biodistribution Drug delivery Acute gouty arthritis 0210 nano-technology business
Zdroj:	Drug Development and Industrial Pharmacy. 47:770-777
ISSN:	1520-5762 0363-9045
DOI:	10.1080/03639045.2021.1934865
Popis:	Colchicine (Col) is a drug used mainly for prevention and treatment of acute gouty arthritis. Unfortunately, colchicine has a narrow therapeutic index, with no obvious differentiation between toxic...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3315cf64093674c7f6c215fb1df6d1de https://doi.org/10.1080/03639045.2021.1934865 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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