Regioselective Hydrolysis of Cocaine and A Convenient Acylation Procedure by Benzoylecgonine

Autor:	F. Martinet, Alain Tomas, Ch. Pham Huy, H. Galons, J. M. Scherrmann
Rok vydání:	1997
Předmět:	Reaction conditions Acylation Hydrolysis chemistry.chemical_compound Chemistry Organic Chemistry Ecgonine methyl ester Benzoylecgonine Regioselectivity Organic chemistry
Zdroj:	Synthetic Communications. 27:3485-3490
ISSN:	1532-2432 0039-7911
DOI:	10.1080/00397919708005651
Popis:	Regioselective hydrolysis of cocaine led, according to the reaction conditions, either to benzoylecgonine or to ecgonine methyl ester. Acylation with benzoylecgonine was readily achieved when benzotriazolyloxytrisdimethylamino-phosphonium (BOP) was used as a coupling agent.
Databáze:	OpenAIRE
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