Serum calcium and phosphorus levels in patients of HIV positive under the treatment
Autor: | N Asha Kiran, M. Ravi Kanth, P. S Girish Kumar, V A R Satyannarayana |
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Rok vydání: | 2020 |
Předmět: |
Bone mineral
medicine.medical_specialty Kidney Tuberculosis Phosphorus Human immunodeficiency virus (HIV) chemistry.chemical_element 030209 endocrinology & metabolism Calcium medicine.disease medicine.disease_cause Gastroenterology 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure chemistry Heart failure Internal medicine Diabetes mellitus medicine 030212 general & internal medicine |
Zdroj: | International Journal of Clinical Biochemistry and Research. 7:164-167 |
ISSN: | 2394-6377 2394-6369 |
DOI: | 10.18231/j.ijcbr.2020.035 |
Popis: | Background: The abnormal levels of serum calcium and phosphorus are mostly seen in diseases of bone, kidney, tuberculosis, parathyroid diseases etc. The present study is aimed to measure the serum total calcium and phosphorous levels in HIV infected patients and in healthy controls. Materials and Methods: This cross sectional case-control study was conducted at Department of Biochemistry, NRI Medical College and General Hospital, Chinnakakani, Guntur, AndhraPradesh. A total of 90 HIV positive patients were taken as cases and 90 healthy subjects served as controls. Patients with congestive heart failure, liver diseases, diabetes and hypertension were excluded from the study. Seropositivity of all 90 HIV patients was confirmed by HIV TRI-DOT test. 5 ml of venous blood sample was collected after taking aseptic precautions from the study subjects. Serum was used for theestimation of Calciumby O-Cresolphthalein complexone method and Phosphorus by Fiske and Subbarow Method. Results: In this study, HIV positive patients had significantly reduced mean serum calcium (8.020.86 mg/dl) and phosphorous (2.680.65 mg/dl) levels compared with healthy subjects. Conclusion: The present study may conclude that serum levels of calcium and phosphorus were decreased in HIV positive patients, suggesting that the levels of calcium and phosphorous should be closely monitored. Keywords: Highly active anti-retroviral therapy, Anti-retroviral therapy, Human immunodeficiency virus, Bone mineral density. |
Databáze: | OpenAIRE |
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