Ligand Characterization of Covalently Functionalized Mesoporous Silica Nanoparticles: An NMR Toolbox Approach
| Autor: | Sean E. Lehman, Sarah C. Larsen, S. V. Santhana Mariappan, Paul S. Mueller, Yulia Tataurova |
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| Rok vydání: | 2014 |
| Předmět: |
Chemistry
Nanoparticle Nuclear Overhauser effect Mesoporous silica Surfaces Coatings and Films Electronic Optical and Magnetic Materials Mesoporous organosilica General Energy Adsorption Chemical engineering Proton NMR Molecule Organic chemistry Physical and Theoretical Chemistry Two-dimensional nuclear magnetic resonance spectroscopy |
| Zdroj: | The Journal of Physical Chemistry C. 118:29943-29951 |
| ISSN: | 1932-7455 1932-7447 |
| Popis: | Mesoporous silica materials are undergoing rapid development for numerous environmental and biomedical applications. These materials are commonly functionalized with small organic molecules through a reaction between an organosilane and the surface silanols. Despite widespread use and implementation of these materials, ligands on their surfaces are challenging to characterize, particularly in aqueous environments. Employing traditional physicochemical characterization methods such as adsorption isotherms, X-ray diffraction, and electron microscopy, as well as solution-phase 1H NMR methods including one-dimensional NMR, diffusion ordered spectroscopy (DOSY) and two-dimensional nuclear Overhauser effect spectroscopy (NOESY), the labile nature of several different surface ligands on mesoporous silica nanoparticles is revealed. The data presented indicate a dynamic model of organosilane release from the surface, and adsorption of the released molecules is ultimately dependent on the nature of the binding of t... |
| Databáze: | OpenAIRE |
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