Histomorphology of Seminal Vesicles Subsequent to Exogenous Neurokinin B Administration in New Zealand White Rabbits
| Autor: | Faiqah Ramzan, Muhammad Haris Ramzan, Zain Ullah |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
010405 organic chemistry Vesicle Lumen (anatomy) Bioengineering Gonadotropin-releasing hormone Biology 01 natural sciences Biochemistry Molecular medicine Epithelium 0104 chemical sciences Analytical Chemistry chemistry.chemical_compound Endocrinology medicine.anatomical_structure chemistry Internal medicine Drug Discovery medicine Molecular Medicine Secretion New zealand white Neurokinin B |
| Zdroj: | International Journal of Peptide Research and Therapeutics. 26:2021-2027 |
| ISSN: | 1573-3904 1573-3149 |
| Popis: | Neurokinin B exists as a member of tachykinin family, which is encoded by Tac3 gene and binds to Tac3R. Several studies have shown that neurokinin B is involved in secretion of gonadotropin releasing hormone and maintenance of reproductive function. No data on the effect of neurokinin B on accessory sex glands is available till date. The current study is designed to determine the dose dependent effects of neurokinin B on seminal vesicles of New Zealand White Rabbits. For experimental procedure, 18 New Zealand white rabbits (Oryctolagus cuniculus) were purchased from National Institute Health, Islamabad Pakistan. Adult laboratory rabbits were administrated with neurokinin B at two different dose concentrations (1 ηg and 1 µg) twice daily for a period of continuous 12 days. The results demonstrated a significant increase in seminal vesicles weight and epithelial cell height at all tested doses (P |
| Databáze: | OpenAIRE |
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