Annulation of pyrrole ring in 4-acylpyridine-3,5-dicarbonitriles in the presence of ammonia

Autor:	Yakov S. Kayukov, O. V. Kayukova, S. V. Karpov, Victor A. Tafeenko, Ekaterina S. Shchegravina, Anastasiya L. Nikiforova, Arthur A. Grigor’ev
Rok vydání:	2019
Předmět:	Annulation Aqueous solution 010405 organic chemistry Organic Chemistry Regioselectivity 010402 general chemistry Ring (chemistry) 01 natural sciences Medicinal chemistry 0104 chemical sciences chemistry.chemical_compound Ammonia chemistry Halogen Pyrrole
Zdroj:	Chemistry of Heterocyclic Compounds. 55:167-171
ISSN:	1573-8353 0009-3122
Popis:	4-Acyl-2-amino-6-chloropyridine-3,5-dicarbonitriles underwent heterocyclization in the presence of ammonia in aqueous dioxane medium, involving the ortho-ketonitrile fragment while preserving the halogen atom. The pyrrole ring annulation process proceeded regioselectively with the formation of a single positional isomer.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::32d9cb367f8040ae07d50412c062c772 https://doi.org/10.1007/s10593-019-02434-4 Zobrazit plný text záznamu Full text from SpringerLink