Associations between ambient fine particulate (PM2.5) exposure and cardiovascular disease: findings from the China Health and Retirement Longitudinal Study (CHARLS)

Autor: Xin Huang, Houfeng Zhou, Tao Yang, Yangyang Li, Xiaowei Mai
Rok vydání: 2021
Předmět:
Zdroj: Environmental Science and Pollution Research. 29:13114-13121
ISSN: 1614-7499
0944-1344
DOI: 10.1007/s11356-021-16541-3
Popis: The evidence regarding the association between long-term fine particulate (PM2.5) exposure and cardiovascular disease (CVD) in developing countries is limited. This study investigated the association between long-term exposure to PM2.5 and the prevalence of CVD among middle-aged and older adults. A total of 13,484 adults ≥ 45 years of age were surveyed in China, and logistic regression models were used to examine the association between PM2.5 and the prevalence of CVD. Furthermore, stratified analyses were conducted to explore potential effect modifiers. In addition, the burden of CVD attributable to PM2.5 was estimated. The analyses revealed that PM2.5 was associated with CVD, with an adjusted odds ratio (OR) of 1.18 (95% confidence interval [CI]: 1.12, 1.26) for each 10 μg/m3 increment in ambient PM2.5. Stratified analyses found that the elderly may be a vulnerable population. It was further estimated that approximately 20.27% (95% CI: 11.86%, 29.96%) of CVD cases could be attributable to PM2.5. This nationwide study confirmed that long-term exposure to PM2.5 was associated with an increased prevalence of CVD in China.
Databáze: OpenAIRE
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