Combination Anthelmintic Treatment for Persistent Ancylostoma caninum Ova Shedding in Greyhounds
| Autor: | Adam J. Rudinsky, Antoinette E. Marsh, Lindie B Hess, Laurie M. Millward, Emily C. Vincent |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
biology
040301 veterinary sciences business.industry 030231 tropical medicine Physiology 04 agricultural and veterinary sciences biology.organism_classification Moxidectin 0403 veterinary science Deworming Praziquantel 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine chemistry Ancylostoma Pyrantel parasitic diseases medicine Anthelmintic Ancylostoma caninum Small Animals business Feces medicine.drug |
| Zdroj: | Journal of the American Animal Hospital Association. 55:160-166 |
| ISSN: | 1547-3317 0587-2871 |
| Popis: | Ancylostoma caninum is a nematode of the canine gastrointestinal tract commonly referred to as hookworm. This study involved eight privately owned adult greyhounds presenting with persistent A. caninum ova shedding despite previous deworming treatments. The dogs received a combination treatment protocol comprising topical moxidectin, followed by pyrantel/febantel/praziquantel within 24 hr. At 7–10 days posttreatment, a fecal examination monitored for parasite ova. Dogs remained on the monthly combination treatment protocol until they ceased shedding detectable ova. The dogs then received only the monthly topical moxidectin maintenance treatment. The dogs remained in the study for 5–14 mo with periodical fecal examinations performed. During the study, three dogs reverted to positive fecal ova status, with two being associated with client noncompliance. Reinstitution of the combination treatment protocol resulted in no detectable ova. Use of monthly doses of combination pyrantel, febantel and moxidectin appears to be an effective treatment for nonresponsive or persistent A. caninum ova shedding. Follow-up fecal examinations were important for verifying the presence or absence of ova shedding despite the use of anthelmintic treatment. Limitations of the current study include small sample size, inclusion of only privately owned greyhounds, and client compliance with fecal collection and animal care. |
| Databáze: | OpenAIRE |
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