The Influence of C936T Gene in Wild of the Vascular Endothelial Growth Factor and Biochemical Variants Analysis for Alpha-Fetoprotein in Hepatocellular Carcinoma Patients in Egypt
Autor: | Soha Hamdy M, Khaled El-Khashab Ae, Gama Tamam H, Sahar Soliman M, Asmaa Rady Am |
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Rok vydání: | 2017 |
Předmět: |
Cancer Research
medicine.medical_specialty Pathology medicine.diagnostic_test business.industry Hepatitis C virus medicine.disease medicine.disease_cause Gastroenterology digestive system diseases symbols.namesake Oncology Abdominal ultrasonography Statistical significance Internal medicine Hepatocellular carcinoma medicine Carcinoma symbols Carcinoid tumour Alpha-fetoprotein business neoplasms Fisher's exact test |
Zdroj: | Journal of Cancer Science & Therapy. |
ISSN: | 1948-5956 |
Popis: | Hepatocellular carcinoma (HCC) is one of the most frequent malignant tumors. It is important to detect disease and recurrence at its earlier period. The aim of this study was to evaluate the influence of the C936T polymorphism of the VEGF and Alfa feto-Protein (AFP) on Hepatocellular carcinoma (HCC), Hepatitis C Virus (HCV) and control groups. Also, estimation of serum AFP and correlation with other parameters was studied. In this study was included 75 subjects, 25 patients with HCV, 25 patients with confirmed HCC and 25 healthy volunteers were subjected to abdominal ultrasonography, AFP and VEGF were assessed. The statistical analysis will include the Fisher exact test, T test and the multivariate regression, with significance level P |
Databáze: | OpenAIRE |
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