Characterization of Selected Pharmaceutical Micropollutants in River Water Using In-Situ Suspended Aggregate Microextraction and Field Enhancement Sample Injection-Capillary Electrophoresis

Autor:	Zulkifli Yusof, Ambavaram Vijaya Bhaskar Reddy, Nur Hidayati Jamil, Zaiton Abdul Majid, Azmi Aris, Jafariah Jaafar
Rok vydání:	2019
Předmět:	Detection limit In situ Analyte Ammonium bromide Aggregate (composite) Chromatography Health Toxicology and Mutagenesis Extraction (chemistry) Toxicology Pathology and Forensic Medicine chemistry.chemical_compound Capillary electrophoresis Pulmonary surfactant chemistry Law Mathematics
Zdroj:	Indian Journal of Forensic Medicine & Toxicology. 13:458
ISSN:	0973-9130 0973-9122
Popis:	A new sample preconcentration technique known as in-situ suspended aggregate microextraction (iSAME) was used for the extraction of acetaminophen, ibuprofen, indomethacine, ciprofloxacin and diclofenac in river waters. The iSAME has been optimized in terms of surfactants selection and concentration, sample volume and extraction time. A combined surfactant of hexadecyltrimethyl ammonium bromide (CTAB) with 5-sulfosalicylic acid dihydrate (SSA) was studied to attain better extraction recoveries for the targeted pharmaceuticals. The separation of analytes was performed using capillary electrophoresis (CE) with online preconcentration by field enhancement sample injection (FESI) mode. The linearity, detection limits and recoveries were recorded and the sensitivity increased with enhancement factor of 11-140 folds. The developed method was successfully applied for the detection of selected pharmaceuticals in river water samples.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::328e63a370eabc08ab8618c609cd655a https://doi.org/10.5958/0973-9130.2019.00332.3 Zobrazit plný text záznamu