Severe Acute Respiratory Syndrome Coronavirus 2 Evolution and Escape From Combination Monoclonal Antibody Treatment in a Person With HIV

Autor: Dara Khosravi, Hannah Soloff, Rose M Langsjoen, Andrei Bombin, Colleen F Kelley, Susan M Ray, Clifford J Gunthel, Brian C Zanoni, Phuong-Vi Nguyen, Jesse J Waggoner, Yun F Wang, Valeria D Cantos, Anne Piantadosi
Rok vydání: 2023
Předmět:
Zdroj: Open Forum Infectious Diseases. 10
ISSN: 2328-8957
Popis: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) escape from combination monoclonal antibody treatment is rarely reported. We describe an immunocompromised individual with human immunodeficiency virus and persistent SARS-CoV-2 infection in whom substantial SARS-CoV-2 evolution occurred, including the emergence of 2 mutations associated with escape from the monoclonal antibody cocktail received.
Databáze: OpenAIRE