Organization: Type of Grafts, Conservation, Regulation

Autor: H Aagaard, Pablo Eduardo Gelber
Rok vydání: 2016
Předmět:
Zdroj: Surgery of the Meniscus ISBN: 9783662491867
DOI: 10.1007/978-3-662-49188-1_47
Popis: The demand for meniscal allografts has recently increased due to the extended indications for meniscus allografting. It is still a matter of debate the more appropriate technique to preserve menisci allografts in an acceptable condition until transplantation. When looking for a graft to be transplanted, one must wonder which properties the preserved tissue should possess if it is going to work for the patient. Does it have to contain metabolizing cells that are capable of cell division or not? Does it have to maintain its architectural indemnity to function properly or not? The meniscus is mainly an avascular structure. Its mid-substance nutrition is fed by solute diffusion from the periphery through the interfibrillar space. It was demonstrated that an abnormally higher interfibrillar space leads to a decrease in solute diffusion [27]. Subsequently, it seems logical to look for a storage technique that produces no change or minimal changes in the menisci’s collagen architecture.
Databáze: OpenAIRE