Highly Regio- and stereoselective formation of 2-hydroxy-5,6-dihydro-2H-1,4-oxazines. An X-ray and 13C NMR study

Autor:	Jean Claude Daran, Norberto Farfán, Rosa Santillan, Sabine Halut, María de Jesus Rosales, Efrén V. García-Báez, Aurelio Ortiz
Rok vydání:	1995
Předmět:	chemistry.chemical_classification Structure analysis Stereochemistry Organic Chemistry X-ray Oxazines Carbon-13 NMR Catalysis Stereocenter Inorganic Chemistry chemistry Yield (chemistry) Stereoselectivity Physical and Theoretical Chemistry
Zdroj:	Tetrahedron: Asymmetry. 6:2715-2722
ISSN:	0957-4166
DOI:	10.1016/0957-4166(95)00361-r
Popis:	(−)-Norephedrine and (−)-norpseudoephedrine undergo condensation with a wide variety of 1,2-diketones to yield the corresponding 2-hydroxy-5,6-dihydro-2H-1,4-oxazines with high regio- and stereoselectivity. The X-ray structure analysis of five of the compounds studied shows that the stereochemistry at the newly formed stereogenic center is S in all cases.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::321f26e363a307c261c57f9c62964c0f https://doi.org/10.1016/0957-4166(95)00361-r Zobrazit plný text záznamu Full Text from ScienceDirect