The effectiveness of iodine prophylaxis when delayed: implications for emergency planning
| Autor: | M D Kovari, M E Morrey |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
medicine.medical_specialty
education.field_of_study business.industry Population Thyroid Public Health Environmental and Occupational Health chemistry.chemical_element General Medicine Iodine medicine.disease Countermeasure medicine.anatomical_structure chemistry Emergency medicine Medicine Emergency planning Medical emergency business education Waste Management and Disposal |
| Zdroj: | Journal of Radiological Protection. 14:345-348 |
| ISSN: | 1361-6498 0952-4746 |
| Popis: | Emergency plans for accidents involving releases of radioiodine often include adminstering stable iodine as a countermeasure. If taken shortly before, or at the same time as, exposure to airborne radioiodine, this almost completely blocks the uptake of radioiodine by the thyroid. However, if the tablets are not taken until some hours after exposure, the protection will be reduced. This paper reviews one major factor affecting the rate at which the effectiveness is reduced: the rate at which iodine is taken up by the thyroid after it reaches the bloodstream, and the variations in this rate between individuals. An important finding is that for a substantial fraction of the population the rate of uptake may be greater than implied in some publications. However, the effectiveness of stable iodine as a countermeasure is also influenced by other factors, such as the duration of the release. These factors are also discussed, together with the overall implications for emergency planning. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|