Photodynamic therapy dosimetry by fluorescence and reflectance spectroscopies
Autor: | William J. Cottrell, Allan R. Oseroff, Thomas H. Foster |
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Rok vydání: | 2004 |
Předmět: | |
Zdroj: | Frontiers in Optics 2004/Laser Science XXII/Diffractive Optics and Micro-Optics/Optical Fabrication and Testing. |
Popis: | Instrumentation is developed for real-time determination of photodynamic therapy dosimetry in vivo, employing measurements of fluorescence emission spectra corrected for effects of dynamic tissue optical properties using white light diffuse reflectance. This system accurately measures photosensitizer photobleaching, photoproduct formation, and tissue oxygenation, all of which are useful as dose metrics. |
Databáze: | OpenAIRE |
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