The primary pharmacology of ceftazidime/avibactam: resistancein vitro

Autor: Wright W Nichols, Sushmita D Lahiri, Patricia A Bradford, Gregory G Stone
Rok vydání: 2023
Předmět:
Zdroj: Journal of Antimicrobial Chemotherapy. 78:569-585
ISSN: 1460-2091
0305-7453
Popis: This article reviews resistance to ceftazidime/avibactam as an aspect of its primary pharmacology, linked thematically with recent reviews of the basic in vitro and in vivo translational biology of the combination (J Antimicrob Chemother 2022; 77: 2321–40 and 2341–52). In Enterobacterales or Pseudomonas aeruginosa, single-step exposures to 8× MIC of ceftazidime/avibactam yielded frequencies of resistance from
Databáze: OpenAIRE