GW28-e1067 Urotensin II induces endothelial-mesenchymal transition of cardiac microvascular endothelial cells via endoplasmic reticulum stress

Autor:	Fan Zheng, Wenbin Xia, Da Chen, Lihua Ji, Xiaoying Zheng, Jinyao Zhong, Yu-Qiang Cui, Yonggang Zhang
Rok vydání:	2017
Předmět:	Transition (genetics) business.industry Endoplasmic reticulum Mesenchymal stem cell medicine.disease Cell biology Stress (mechanics) chemistry.chemical_compound chemistry Fibrosis medicine Unfolded protein response Cardiology and Cardiovascular Medicine Urotensin-II business
Zdroj:	Journal of the American College of Cardiology. 70:C42
ISSN:	0735-1097
DOI:	10.1016/j.jacc.2017.07.146
Popis:	Recent studies suggest that endothelial-mesenchymal transition (EndMT) as a link between endoplasmic reticulum stress (ER stress) and fibrosis. We previous found that urotensin II (UII) could promote EndMT in cardiac microvascular endothelial cells of rats. Therefore, in the present study, we
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::31fc479c2bf5c6e5f4e8102e6ee527ba https://doi.org/10.1016/j.jacc.2017.07.146 Zobrazit plný text záznamu