ChemInform Abstract: Reactions of Oxetan-3-tert-butylsulfinimine for the Preparation of Substituted 3-Aminooxetanes

Autor: Jason D. Brubaker, Philip J. Hamzik
Rok vydání: 2010
Předmět:
Zdroj: ChemInform. 41
ISSN: 1522-2667
0931-7597
Popis: The oxetane ring is useful in drug discovery as a bioisostere for both the geminal dimethyl group and the carbonyl group. A convenient, straightforward approach to access structurally diverse 3-aminooxetanes through the reactivity of oxetan-3-tert-butylsulfinimine and the corresponding sulfinylaziridine is described.
Databáze: OpenAIRE