CLINCO-MICROBIOLOGICAL PROFILE OF RHINOSINUSITIS IN ADULTS
| Autor: | Rahul Kawatra, Puneet Maheshwari, Anjali Agarwal, Salwa Salam |
|---|---|
| Rok vydání: | 2023 |
| Předmět: |
Linguistics and Language
Histology Mechanical Engineering General Chemical Engineering General Mathematics Organic Chemistry Metals and Alloys General Engineering General Physics and Astronomy General Chemistry General Medicine Condensed Matter Physics Biochemistry Industrial and Manufacturing Engineering Language and Linguistics Analytical Chemistry General Energy Oncology Materials Chemistry Physical and Theoretical Chemistry General Pharmacology Toxicology and Pharmaceutics General Agricultural and Biological Sciences Spectroscopy |
| Zdroj: | INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH. :66-69 |
| DOI: | 10.36106/ijsr/4516832 |
| Popis: | Introduction: Rhinosinusitis is the condition in which sinonasal mucosa inside the paranasal sinuses gets inamed and its clinical manifestation is represented by various sinonasal and extra-nasal symptoms. Hence, the present study was planned with an aim to study the clinic-microbial prole of rhinosinusitis in adults. This cross-sectional analytical study included 300 rhi Methodology: nosinusitis patients. Detailed clinical and demographic data were collected. All the patients underwent plain radiography to assess the sinus involvement. Nasal endoscopy was performed in all the cases. During nasal endoscopy, nasal swabs were collected from all the patients. For all the culture positive cases, antibiotic susceptibility assessment was done. The majority of cultures (61.3%) were negative for pathogens. 34% ha Results: d a positive bacterial pathogen culture, while 4.7% had a positive fungal culture. Methicillin-resistant Staphylococcus aureus (MRSA) was the most prevalent gramme-positive isolate (55.9%). Simultaneously, Citrobacter spp. (3.9%) was the most prevalent gramme-negative isolate. Candida spp. accounted for 71.4% of the fourteen positive fungal specimens, while Aspergillus avus accounted for the remaining 28.6%. The majority of patients were only administered antibiotics. Cefoperazone-Sulbactam, Linezolid, Piperacillin-tazobactam, Cefritaxeone, Tobramycin, Meropenem, and Clindamycin exhibited one hundred percent sensitivity. The three most resistant antibiotics used in more than half specimen were Tetracycline (60.7%), Erythromycin (17.4%) and Penicillin (13.7%) respectively. The most prevalent organism causing rhinosinusitis was Conclusion: found to be Staphylococcus aureus and most sensitive antibiotics were Cefoperazone-Sulbactam, Linezolid, Piperacillin-tazobactam, Cefritaxeone, Tobramycin, Meropenem, and Clindamycin. |
| Databáze: | OpenAIRE |
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