Comparison of Hyperpolarized 3He and 129Xe MR Imaging in Cystic Fibrosis Patients
| Autor: | Kun Qing, F. William Hersman, Jamie Mata, Iulian C. Ruset, Talissa A. Altes, John P. Mugler, Craig H. Meyer, Robert P. Thomen, Ummul Afia Shammi, Michelle Felicia D'Alessandro |
|---|---|
| Rok vydání: | 2022 |
| Předmět: |
Reproducibility
Lung medicine.diagnostic_test business.industry Magnetic resonance imaging computer.software_genre medicine.disease Cystic fibrosis Mr imaging 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Voxel 030220 oncology & carcinogenesis medicine Radiology Nuclear Medicine and imaging In patient Nuclear medicine business computer Lung function |
| Zdroj: | Academic Radiology. 29:S82-S90 |
| ISSN: | 1076-6332 |
| DOI: | 10.1016/j.acra.2021.01.007 |
| Popis: | PURPOSE In this study, we compared hyperpolarized 3He and 129Xe images from patients with cystic fibrosis using two commonly applied magnetic resonance sequences, standard gradient echo (GRE) and balanced steady-state free precession (TrueFISP) to quantify regional similarities and differences in signal distribution and defect analysis. MATERIALS AND METHODS Ten patients (7M/3F) with cystic fibrosis underwent hyperpolarized gas MR imaging with both 3He and 129Xe. Six had MRI with both GRE, and TrueFISP sequences and four patients had only GRE sequence but not TrueFISP. Ventilation defect percentages (VDPs) were calculated as lung voxels with |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|