Metal-free dearomatization reactions of naphthol-ynamides for the divergent and enantioselective synthesis of azaspirocycles
| Autor: | Hang-Hao Li, Yi-Ping Zhang, Tong-Yi Zhai, Bin-Yang Liu, Chong-Yang Shi, Jin-Mei Zhou, Long-Wu Ye |
|---|---|
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Organic Chemistry Frontiers. 9:3709-3717 |
| ISSN: | 2052-4129 |
| DOI: | 10.1039/d2qo00685e |
| Popis: | An efficient Brønsted acid (BA) catalyzed intramolecular dearomatization cyclization of naphthol-ynamides has been developed, enabling the practical and divergent synthesis of two azaspirocycles in high yields. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|