Effects of Hyperbaric Oxygenation on Metabolism III. Succinic Dehydrogenase, Acid Phosphatase, Cathepsin and Soluble Nitrogen

Autor:	Aaron P. Sanders, I. H. Hall
Rok vydání:	1966
Předmět:	Cathepsin chemistry.chemical_classification Succinic dehydrogenase biology Acid phosphatase chemistry.chemical_element Metabolism Oxygen General Biochemistry Genetics and Molecular Biology Soluble nitrogen Enzyme Biochemistry chemistry Toxicity biology.protein
Zdroj:	Experimental Biology and Medicine. 121:1203-1206
ISSN:	1535-3699 1535-3702
DOI:	10.3181/00379727-121-31005
Popis:	Summary1. Succinic dehydrogenase, ca-thepsin and acid phosphatase activities and soluble and total nitrogen were determined in homogenates of the cerebral hemispheres, liver and kidney from rats previously exposed to normal air, and 100% oxygen for 2 hours at 1 and 3 atmospheres, and for 11/2 hours at 5 atmospheres. 2. HPO caused a decrease of succinic dehydrogenase activity and an increase in free lysosomal enzymatic activities with increasing pressure. 3. There was a slight decrease in percent soluble nitrogen at 1 and 3 atmospheres, and a marked increase at 5 atmospheres. 4. Increased free lysosomal enzyme activities and subsequent solubilization of protein structures are major destructive factors in high pressure oxygen toxicity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::31d4f04ff2e052820af2e08fa00a9d66 https://doi.org/10.3181/00379727-121-31005 Zobrazit plný text záznamu