| Autor: |
Muhammed Iqbal Choudhary, Y. Tsuda, Mohammed Nabeel Ghayur, Takuro Maruyama, Kiran Iqbal, Ahmed Abbaskhan, Zeba Parween, Anwarul Hassan Gilani, Farzana Shaheen |
| Rok vydání: |
2011 |
| Předmět: |
|
| Zdroj: |
Phytotherapy Research. 26:783-786 |
| ISSN: |
0951-418X |
| DOI: |
10.1002/ptr.3600 |
| Popis: |
In continuation of our work on Indian celery (Seseli diffusum (Roxb. ex Sm.) Santapau & Wagh; Umbelliferae), the fractionation of the 80% MeOH–H2O extract of the seeds was performed to identify the principles responsible for its folk use as an antispasmodic and diuretic. Several compounds were isolated as active components: seselin (1) and anthriscinol methyl ether (4) showed a selective cytotoxicity to some yeast strains. Compound 1 also showed spasmolytic activity. On the other hand, isopimpinellin (3) and isorutarin (5) exhibited a spasmogenic effect on the smooth muscle preparations. Compound 5 was also found to have antioxidant activity. Among them, compound 4 was isolated for the first time from this plant. Copyright © 2011 John Wiley & Sons, Ltd. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
Plný text