Synthesis of titanium oxide thin films containing antibacterial silver nanoparticles by a reactive magnetron co-sputtering system for application in biomedical implants

Autor:	Jeon-Geon Han, Doo-Hoon Song, Sieun Kim, Soo-Hyuk Uhm, Kyoung Nam Kim, Jae-Sung Kwon
Rok vydání:	2012
Předmět:	Materials science Biocompatibility Mechanical Engineering Nanoparticle Nanotechnology Condensed Matter Physics Silver nanoparticle Titanium oxide Mechanics of Materials Sputtering Cavity magnetron General Materials Science Thin film Layer (electronics) Nuclear chemistry
Zdroj:	Materials Research Bulletin. 47:2994-2998
ISSN:	0025-5408
DOI:	10.1016/j.materresbull.2012.04.085
Popis:	Titanium oxide thin films containing silver (Ag) nanoparticles were synthesized on commercially pure titanium (cp-Ti) substrates using a reactive magnetron co-sputtering method. The goal was to maximize bactericidal activity along with sustained biocompatibility. Furthermore, this study examined the correlation between Ag nanoparticle dispersion in the films and the antibacterial efficacy of the Ag ions released from the films. The results showed that there might be two factors affecting the inhibition of bacterial attachment to the surface of the specimens: surface morphology and Ag ion release. MTT assay results demonstrated that there was no cytotoxicity on fibroblast cells in any group. Overall, the magnetron sputtered Ag nanoparticle-containing titanium oxide coatings in this study can be used as an efficient antibacterial layer with sustained biocompatibility.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::31d1c16f988423fbbecf28b0f70414c4 https://doi.org/10.1016/j.materresbull.2012.04.085 Zobrazit plný text záznamu Full Text from ScienceDirect