Supercritical Fluid Extraction Coupled with Solvent-Less Spray Collection Mode for Rapid Separation of Indirubin and Tryptanthrin from Folium Isatidis
| Autor: | Hsin-Hsin Tsao, Hsing-Jung Chen, Kong-Hwa Chiu, Jen-Fon Jen, Jiunn Guang Lo |
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| Rok vydání: | 2011 |
| Předmět: |
Supercritical carbon dioxide
Chromatography Process Chemistry and Technology General Chemical Engineering Extraction (chemistry) Supercritical fluid extraction Filtration and Separation General Chemistry Solvent chemistry.chemical_compound chemistry Yield (chemistry) Folium of Descartes Indirubin Acetonitrile |
| Zdroj: | Separation Science and Technology. 46:972-977 |
| ISSN: | 1520-5754 0149-6395 |
| Popis: | Supercritical carbon dioxide modified with acetonitrile and water for the extraction of indirubin and tryptanthrin from Folium Isatidis and the collection of these two bioactive ingredients by a spray mode are presented in this study. Two pumps, one for the addition of the modifier and the other for the transportation of CO2, were used for supercritical fluid extraction (SFE). This is a fast and environmentally-friendly approach for the production of herbal medicine. Compared to conventional solvent extraction, the yield of bioactive indirubin and tryptanthrin by this SFE process was approximately the same, but with a shorter process time and better protection of the environment. |
| Databáze: | OpenAIRE |
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