Novel neurotrophic sesquiterpene-neolignans from magnolia obovata

Autor:	Mitsuaki Kodama, Hiroshi Okazaki, Takashi Hasegawa, Yukio Otoshi, Yoshiyasu Fukuyama, Masakazu Nagasawa
Rok vydání:	1989
Předmět:	biology Stereochemistry Organic Chemistry Nuclear magnetic resonance spectroscopy Sesquiterpene biology.organism_classification Biochemistry Magnoliaceae chemistry.chemical_compound chemistry Cell culture Drug Discovery biology.protein Magnolia obovata Analysis method Neurotrophin
Zdroj:	Tetrahedron Letters. 30:5907-5910
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(01)93502-6
Popis:	Novel sesquiterpene-neolignans, eudesobovatols A (1) and B (2) isolated from Magnolia obovata have been assigned structures on the basis of detailed spectroscopic analyses and chemical degradation, and eudesobovatol A has been found to exhibit neurotrophic activity at 10 −5 M $$$ 10 −7 M on neuronal cell culture system of fetal rat cerebral hemisphere.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::31914f53af09c6136e83215fd7ba0a8f https://doi.org/10.1016/s0040-4039(01)93502-6 Zobrazit plný text záznamu