Ultrasound-Mediated Therapies Using Receptor-Targeted Nanodroplets
| Autor: | Reena Zutshi, A. Kerschen, Rachel Labell, Terry O. Matsunaga, K. Penrose, E. Unger, Patricia A. Schumann |
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| Rok vydání: | 2006 |
| Předmět: |
Drug
Pathology medicine.medical_specialty Materials science business.industry medicine.medical_treatment media_common.quotation_subject Ultrasound medicine.disease Tumor site Radiation therapy Prostate cancer chemistry.chemical_compound Downregulation and upregulation Paclitaxel chemistry medicine Cancer research business Receptor media_common |
| Zdroj: | AIP Conference Proceedings. |
| ISSN: | 0094-243X |
| DOI: | 10.1063/1.2205529 |
| Popis: | Angiogenic vessels at tumor sites are leaky and allow particles less than 400 nm to pass through. We have developed targeted nanodroplets that are less than 400 nm in size and are capable of encapsulating drug molecules which can be released at the tumor site upon insonation. These nanodroplets are targeted to the α6β1 receptor, which is upregulated in prostate cancer. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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