Changes in the Time-Domain of Heart Rate Variability and Corticosterone after Surgical Trauma to the Nasal Septum in Rats
Autor: | I. V. Kastyro, V. I. Popadyuk, S. G. Dragunova, Igor V. Reshetov, T. F. Kosyreva, P. E. Shmaevsky, G. V. Khamidulin, M. G. Kostyaeva |
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Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
business.industry medicine.medical_treatment Biophysics General Chemistry General Medicine Biochemistry Septoplasty chemistry.chemical_compound medicine.anatomical_structure chemistry Corticosterone Power index Internal medicine Control data Blood plasma medicine Cardiology Nasal septum Heart rate variability business Blood sampling |
Zdroj: | Doklady Biochemistry and Biophysics. 499:247-250 |
ISSN: | 1608-3091 1607-6729 |
DOI: | 10.1134/s1607672921040098 |
Popis: | The aim of the work was to study changes in the time range of heart rate variability (HRV) against the background of changes in the concentration of corticosterone in blood plasma in rats after surgical trauma to the nasal septum. Septoplasty was simulated in 30 mature male Wistar rats weighing 210-290 g. ECG was recorded with subsequent analysis of the time domain of HRV, as well as blood sampling to estimate changes in the concentration of corticosterone in the blood plasma was performed. As a result, SDNN significantly increased in comparison with the control on days 2 and 3 (p < 0.001) but decreased on days 4-5 (p < 0.001) and 6 (p < 0.01). rMSSD changed in waves with two irregular peaks on days 1 and 6. SDNN/rMSSD, in comparison with the 1st day of the postoperative period, increased on the 2nd day, continued to increase (p |
Databáze: | OpenAIRE |
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