Changes in the Time-Domain of Heart Rate Variability and Corticosterone after Surgical Trauma to the Nasal Septum in Rats

Autor: I. V. Kastyro, V. I. Popadyuk, S. G. Dragunova, Igor V. Reshetov, T. F. Kosyreva, P. E. Shmaevsky, G. V. Khamidulin, M. G. Kostyaeva
Rok vydání: 2021
Předmět:
Zdroj: Doklady Biochemistry and Biophysics. 499:247-250
ISSN: 1608-3091
1607-6729
DOI: 10.1134/s1607672921040098
Popis: The aim of the work was to study changes in the time range of heart rate variability (HRV) against the background of changes in the concentration of corticosterone in blood plasma in rats after surgical trauma to the nasal septum. Septoplasty was simulated in 30 mature male Wistar rats weighing 210-290 g. ECG was recorded with subsequent analysis of the time domain of HRV, as well as blood sampling to estimate changes in the concentration of corticosterone in the blood plasma was performed. As a result, SDNN significantly increased in comparison with the control on days 2 and 3 (p < 0.001) but decreased on days 4-5 (p < 0.001) and 6 (p < 0.01). rMSSD changed in waves with two irregular peaks on days 1 and 6. SDNN/rMSSD, in comparison with the 1st day of the postoperative period, increased on the 2nd day, continued to increase (p
Databáze: OpenAIRE
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