Popis: |
The proton magnetic resonance spectrum of malignant cells can frequently be distinguished from that of normal tissue by the presence of high-resolution signals consistent with lipid (1, 2). Such signals are unlikely to arise from bilayer phospholipids, which are considerably restricted in their motion, unless they are oriented at the magic angle (3, 4). We have shown that the contribution of the high-resolution lipid signals to the total proton spectrum is proportional to the neutral lipid content of the cell (5, 6)... |