Neutrophil to lymphocyte ratio as the main predictor of peripheral artery disease in regular hemodialysis patients
| Autor: | R A Muzasti, R H Siregar |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.medical_treatment fungi Type 2 Diabetes Mellitus Disease medicine.disease Systemic inflammation Gastroenterology medicine.anatomical_structure Internal medicine medicine Hemodialysis medicine.symptom Ankle Neutrophil to lymphocyte ratio business Dialysis Kidney disease |
| Zdroj: | IOP Conference Series: Earth and Environmental Science. 125:012109 |
| ISSN: | 1755-1315 1755-1307 |
| DOI: | 10.1088/1755-1315/125/1/012109 |
| Popis: | Cardiovascular disease is the most inducer of morbidity and mortality of chronic kidney disease (CKD) patients who have undergone dialysis. Today, neutrophil to lymphocyte ratio (NLR) is considered an indicator of the severity and extent of systemic inflammation and atherosclerosis in patients with renal and cardiovascular disorders. To examine the relationship between NLR with PAD in regular hemodialysis patients, a cross-sectional study, Ankle- Brachial Index (ABI) measurement and peripheral blood examination was on 72 regular hemodialysis patients ≥6 months. The ABI value ≤0.9 is considered PAD. NLR≥ 3.5 is considered abnormal based on some pre-existing research. Prevalence of PAD is 29.16%. Chi- square test showed significant correlation between NLR with PAD (p = 0.0001), multiplication of Calcium and Phosphorus (p = 0.0001), and type 2 Diabetes Mellitus (T2DM) (p = 0.039), multivariate analysis showed that NLR was an independent predictor for PAD in regular hemodialysis patients (RR = 2.271 p = 0.027). In conclusion, NLR, a new inflammatory marker of peripheral blood examination may serve as a marker of PAD in a regular hemodialysis patient, in addition to the multiplication of Calcium and Phosphorus as well as T2DM. |
| Databáze: | OpenAIRE |
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