N,N′-Di-Boc-Substituted Thiourea as a Novel and Mild Thioacylating Agent Applicable for the Synthesis of Thiocarbonyl Compounds

Autor:	Biaolin Yin, Zheng-Rong Li, Jiancun Zhang, Zhaogui Liu
Rok vydání:	2010
Předmět:	chemistry.chemical_compound chemistry Nucleophile Thiourea Sodium Organic Chemistry Functional group chemistry.chemical_element Trifluoroacetic acid anhydride Selectivity Medicinal chemistry Catalysis
Zdroj:	Synthesis. 2010:991-999
ISSN:	1437-210X 0039-7881
Popis:	Stable and readily available N,N'-di-Boc-substituted thiourea, when activated with trifluoroacetic acid anhydride, was used as a novel thioacylating agent. Through the thioacylation of nucleophiles, such as amines, alcohols, thiols, sodium benzenethiolate, and sodium malonates with N,N'-di-Boc-substituted thiourea, a series of thiocarbonyl compounds were prepared under mild conditions with good chemical selectivity and functional group tolerance.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::314ff65d3b5ce9332a99c8aea40c1ad6 https://doi.org/10.1055/s-0029-1219273 Zobrazit plný text záznamu