Clinical usefulness of eosinopenia in differentiating COVID-19 versus other flu-like illness in outpatient set-up
| Autor: | R. Anand, T. Dhanasekar, V. G. Vinod, C. Chandrasekar, B. Rajagopalan, M. Koushik Muthu Raja |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19) medicine.diagnostic_test business.industry Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Case-control study Complete blood count General Medicine medicine.disease General Biochemistry Genetics and Molecular Biology Pneumonia Internal medicine medicine Eosinopenia Infectious disease (athletes) business Flu-like illness |
| Zdroj: | Biomedicine. 41:498-501 |
| ISSN: | 0970-2067 |
| DOI: | 10.51248/.v41i2.1066 |
| Popis: | Introduction and Aim:Corona virus disease 2019 (Covid-19) is a highly infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 has affected over 200 countries and territories. The aim of the present study is to evaluate the role of eosinopenia in differentiating COVID-19 suspect from other flu-like illnesses in an outpatient setting. Materials and Methods:It was a retrospective case control study in which data of 1252 suspected COVID 19 patients who visited the fever clinic were enrolled. Among this, 701 patients were found to have COVID-19 pneumonia and 551 had other flu-like illnesses. CBC (complete blood count) and CRP(C- reactive protein) were taken in all patients along with chest x-ray as routine protocol. Results:Among the 701 positive patients, eosinopenia was seen in 527 patients and had a sensitivity of 75.2 % and specificity of 68.6 %. When combined with other lab parameters such as the increased CRP and lymphopenia, the specificity rises up to 78.6 %. Conclusion:Our study shows that eosinopenia as an independent variable, is a reliable marker to differentiate COVID-19 suspect patients from other flu-like illnesses on outpatient basis, however when combined with other parameters like lymphopenia and CRP the specificity increases further. |
| Databáze: | OpenAIRE |
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