Investigation of the Inhibition of Cyanide on Metabolism of Fish Liver Mitochondria by Microcalorimetry

Autor:	Cai-Qin Qin, Zhong-Hai Zhang, Jie Dai, S. S. Qu, Yi Liu, Huirong Li
Rok vydání:	2006
Předmět:	Isothermal microcalorimetry biology Cyanide Aquatic animal General Chemistry Metabolism Mitochondrion biology.organism_classification Cyprinus chemistry.chemical_compound chemistry Biochemistry Respiration Sodium cyanide
Zdroj:	Chinese Journal of Chemistry. 24:627-630
ISSN:	1614-7065 1001-604X
DOI:	10.1002/cjoc.200690120
Popis:	A microcalorimetric technique based on the metabolic heat-output was explored to evaluate the inhibition of cyanide on the mitochondrial metabolism of aquatic animal, Cyprinus carpio. The power-time curves could be divided into four parts:lag phase, active recovery phase, stationary phase, and decline phase, and the corresponding thermokinetic parameters were obtained. The maximum heat production rate Pmax decreased in a linear manner with the increase of concentration of cyanide, however, such mitochondria of aquatic animal were still metabolized actively even under the action of high concentration of cyanide. All the observations suggested that the mitochondria of this aquatic animal should exhibit considerable ability of cyanide-resistant respiration.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3128bc903d7efbe1484f8a8d2f99de27 https://doi.org/10.1002/cjoc.200690120 Zobrazit plný text záznamu Plný text