Typical electronegative electroretinography and nyctalopia as a presenting feature of systemic malignant melanoma
| Autor: | Kakarla V. Chalam, Abby Vercio, Timothy Winter |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Visual acuity genetic structures medicine.diagnostic_test business.industry Melanoma General Medicine Fundus (eye) medicine.disease Occult eye diseases Nyctalopia medicine.anatomical_structure Ophthalmology medicine sense organs medicine.symptom business Pelvis Electroretinography Retinopathy |
| Zdroj: | International Medical Case Reports Journal. 12:265-276 |
| ISSN: | 1179-142X |
| DOI: | 10.2147/imcrj.s201500 |
| Popis: | We report a unique case of a female who presented with unilateral disk edema, melanoma-associated retinopathy symptoms, and suggestive electroretinography findings preceding a diagnosis of metastatic melanoma of the pelvis. A 63-year-old female presented with complaints of seeing shimmering lights and nyctalopia, and underwent an extensive ophthalmological and electrophysiological examination. Best-corrected visual acuity was 20/20 in both eyes. Visual fields showed relative central scotomata and concentric narrowing. Slit-lamp and fundus examinations were normal. Rod-specific electroretinography responses were severely reduced, with electronegative maximal combined rod-cone responses and delayed cone responses with normal amplitude. Melanoma-associated retinopathy was suspected. Extensive systemic and internal evaluation revealed occult metastatic melanoma of the pelvis of unknown primary site. |
| Databáze: | OpenAIRE |
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