Identification of hepatitis C virus (HCV) genotypes in infected patients from the west of Mexico
| Autor: | Matsui Osmar, Armendariz-Borunda Juan, Campollo Octavio, Arturo Panduro, Rivas-Estilla A Marı́a, Sánchez L. Verónica, Segura-Ortega J Enrique |
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| Rok vydání: | 1998 |
| Předmět: |
education.field_of_study
Hepatology biology Hepatitis C virus Hepacivirus Population virus diseases medicine.disease medicine.disease_cause biology.organism_classification Virology digestive system diseases Flaviviridae Infectious Diseases Genotype Coinfection medicine Viral disease Risk factor education |
| Zdroj: | Hepatology Research. 12:121-130 |
| ISSN: | 1386-6346 |
| Popis: | Information about genotypes and associated risk factors in hepatitis C virus (HCV) infected patients in Latin America is limited. The aim of this study was to identify the HCV genotypes and associated risk factors in a group of HCV infected patients from the west of Mexico. Genotyping analysis was performed in 90 patients with positive anti-HCV and HCV-RNA. Genotypes 1 and 2 were found in 61 (67.8%) and 28 (31.1%) patients, respectively, and one with 4c/d genotype (1.1%). The most frequent HCV genotype was 1a (42.2%), followed by 1b (21.1%) and 2a/c (20%). Coinfection was present in 6.6% in a similar population with genotypes 1a and 1b or with 2a/c and 2b. The most frequent associated risk factor was blood transfusion in 57.8% of cases. However, there was no statistically significant difference between the risk factors analyzed and the acquisition of HCV infection. |
| Databáze: | OpenAIRE |
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