Effect of Celox® Powder on Initial Hemostasis After Cardiac Catheterization in Pediatric Patients with Congenital Heart Disease: A Prospective Study
| Autor: | Nima Mehdizadegan, Hamid Mohammadi, Sajad Shabanpuor-Haghighi, Gholamhossein Ajami, Kambiz Keshavarz, Tahmineh Zafari, Saeed Abtahi, Pouria Moradi, Mohammad Reza Edraki, Hamid Amoozgar |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Venipuncture Coagulation time Heart disease business.industry medicine.medical_treatment 030208 emergency & critical care medicine medicine.disease Surgery 03 medical and health sciences Pediatric patient 0302 clinical medicine 030225 pediatrics Hemostasis Pediatrics Perinatology and Child Health medicine Prospective cohort study business Cardiac catheterization |
| Zdroj: | Iranian Journal of Pediatrics. 30 |
| ISSN: | 2008-2150 2008-2142 |
| DOI: | 10.5812/ijp.95784 |
| Popis: | Background: Ordinary pressure dressing for hemostasis after cardiac catheterization is time consuming and might cause some problems, such as pain or loss of blood, which has to be controlled, particularly in pediatric patient. Using Celox® (chitosan) powder dressing might cause quicker initial hemostasis. Methods: In this prospective study, we assessed Celox® powder among patients in hospitals affiliated with Shiraz University of Medical Sciences, from November 2017 to February 2018. The patients were stratified in two groups. The case group included patients for whom Celox® powder was used along with sterile gauze pressure at the puncture site to achieve hemostasis, and the control group those in whom hemostasis was achieved by standard sterile gauze pressure method. Results: Sixty patients under 16 years of age with congenital heart diseases were evaluated and underwent cardiac catheterization. We stratified the patients in two groups called case (30 patients) and control group (30 patients). Considering both arterial and venous initial hemostasis, in the case group, the minimum and maximum, median and mean coagulation time were less than those in the control group; however, the initial hemostasis was statistically significant only in venipuncture site. Also, the venous coagulation time was shorter among the patients weighing less than 10 kilograms in comparison to those with higher weight. In the case group, using Celox® stirred hemostasis toward the lower percentiles, but based on 50th percentile, the distribution in each group was identical. Conclusions: Celox® powder dressing in children led to reduced coagulation time in venipuncture site, and we might recommend utilizing this type of dressing for venous hemostasis in children after venipuncture. |
| Databáze: | OpenAIRE |
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