The influence of malignancy processes in pancreatic tissue on the formation of optical and infrared spectra in bile and pancreatic juice samples
| Autor: | K.M. Giraev, R. T. Medjidov, M.A. Magomedov, N. A. Ashurbekov, A. A. Murtazaeva |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Absorption (pharmacology) medicine.medical_specialty Chromatography Chemistry Pancreatic tissue Biophysics Infrared spectroscopy Malignancy medicine.disease 01 natural sciences Peroxide Gastroenterology Light scattering 010309 optics 03 medical and health sciences chemistry.chemical_compound 030104 developmental biology medicine.anatomical_structure Internal medicine 0103 physical sciences Pancreatic juice medicine Pancreas |
| Zdroj: | Biophysics. 62:641-649 |
| ISSN: | 1555-6654 0006-3509 |
| DOI: | 10.1134/s0006350917040066 |
| Popis: | The results of optical spectral studies in the wavelength range of 250–1500 nm and frequencies of 6000–400 cm–1 of samples of bile and pancreatic juice with the development of malignancy in the tissues of the pancreas are presented. It was shown that the development of degenerative processes in the studied biological fluids led to an increase in the intensity of the spectral profile of absorption at low frequencies (1600–400 cm–1) and the appearance of a peak near the frequency of 840 ± 5 cm–1 formed by the vibrations of the O–O groups of aliphatic and aromatic peroxides or peroxide acids. It was demonstrated that the development of malignant processes led to an increase and to a decrease of the density and size of particles in the samples of bile and pancreatic juice, respectively, as inferred from the corresponding increase and decrease of the coefficients of absorption and scattering of light. |
| Databáze: | OpenAIRE |
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