Two new flavonol glycosides from Selaginella tamariscina
| Autor: | Jing Wen, Qi-Xuan Wang, Xin-Jia Yan, Wen-Lan Li, Cheng-Dong Nie |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pharmacology
chemistry.chemical_classification 2019-20 coronavirus outbreak Coronavirus disease 2019 (COVID-19) Chemistry Stereochemistry Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Organic Chemistry Pharmaceutical Science Selaginella tamariscina Glycoside General Medicine Analytical Chemistry Complementary and alternative medicine Drug Discovery Molecular Medicine Spectral analysis MTT assay Two-dimensional nuclear magnetic resonance spectroscopy |
| Zdroj: | Journal of Asian Natural Products Research. 24:496-502 |
| ISSN: | 1477-2213 1028-6020 |
| DOI: | 10.1080/10286020.2021.1976160 |
| Popis: | Two new flavonol glycosides 3,5,7-trimethoxyflavone-4'-O-[5'''-O-p-coumaroyl-s-D-apiofuranoyl-(1'''â2'')-s-D-glucopyranoside] (1) and 3,5,7-trimethoxyflavone -4'-O-s-D-glucopyranoside (2) were isolated from Selaginella tamariscina. The structures of 1 and 2 were elucidated on the basis of chemical and spectral analysis, including 1D, 2D NMR analyses and HRESIMS spectrometry. Two compounds were evaluated for cytotoxic activities against A-375, MCF-7, MDA-MB-231 and MDA-MB-468 cell lines by MTT assay. Unfortunately, two compounds displayed no cytotoxic activities. |
| Databáze: | OpenAIRE |
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