Parallel synthesis of oligonucleotides containing N-acyl amino-LNA and their therapeutic effects as anti-microRNAs
| Autor: | Tomo Takegawa-Araki, Kai Yasukawa, Norihiko Iwazaki, Hideto Maruyama, Hiroyuki Furukawa, Hiroaki Sawamoto, Satoshi Obika |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Organic & Biomolecular Chemistry. 20:9351-9361 |
| ISSN: | 1477-0539 1477-0520 |
| DOI: | 10.1039/d2ob01809h |
| Popis: | Efficient oligonucleotide synthesis by post elongation modification with direct acylation of 2′-amino-LNA and evaluation of their microRNA inhibitory activity. |
| Databáze: | OpenAIRE |
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