Antiprotozoal activity ofNeurolaena lobata

Autor:	Ingeborg Berger, Armando Cáceres, Claus M. Passreiter, Wolfgang Kubelka
Rok vydání:	2001
Předmět:	Pharmacology biology medicine.drug_class biology.organism_classification medicine.disease_cause Leishmania Leishmania braziliensis Leishmania mexicana Microbiology Neurolaena Lobata parasitic diseases medicine Antiprotozoal Trichomonas vaginalis Trypanosoma cruzi
Zdroj:	Phytotherapy Research. 15:327-330
ISSN:	0951-418X
Popis:	Extracts, fractions and sesquiterpene lactones from Neurolaena lobata (L.) R. Br. (Asteraceae), a traditional medicinal plant from Guatemala, were tested in vitro against Leishmania spp. promastigotes, Trypanosoma cruzi trypomastigotes and epimastigotes and Trichomonas vaginalis trophozoites. The ethanol extract inhibited the parasite growth of L. mexicana, T. cruzi and T. vaginalis significantly. The pure germacranolides 1 and a mixture of 2 and 3, isolated from the ethonal extract, were highly active against L. mexicana and T. cruzi.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::30fc01b4738f132aad639bf4ea974ccd https://doi.org/10.1002/ptr.782 Zobrazit plný text záznamu Plný text