| Autor: |
Hussam Abu Farsakh, Altaf Ijmail |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
International Clinical Pathology Journal. 4 |
| ISSN: |
2471-0016 |
| DOI: |
10.15406/icpjl.2017.04.00116 |
| Popis: |
The morphological and histochemical changes in nbsp muscle biopsies from cases with myasthenia gravis MG were studied The patients were misdiagnosed at the initial presentation however they were all proved later by either histochmical and serological tests or improvement on mestinone therapy to have MG nbsp Here the histomorphological and histochemical changes that were seen in muscle biopsies of MG with atypical clinical presentation were the followings atrophy of type II fibers predominance of type I fibers increased NADH staining at the neuromuscular junction NMJ The most consistent finding is marked reduction in acetylcholinesterease AChE activity at the end plates in all cases nbsp The results of this study suggest that histochemical and acetyl cholinesterase stains in combination with clinical assessment can help to identify unsuspected cases of MG |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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