ChemInform Abstract: Phenylacetyloxymethylene, a Carboxyl Protecting Group Removable with Immobilized Penicillin Acylase, Useful in Benzyl Penicillin Chemistry

Autor:	Eva Baldaro, Piero Grasselli, Ameriga Lazzarini, Claudio Fuganti, Daniela Faiardi
Rok vydání:	1989
Předmět:	Penicillin Acylase Chemistry Group (periodic table) Side chain medicine Single step General Medicine Protecting group Benzylpenicillin Combinatorial chemistry Benzyl penicillin medicine.drug
Zdroj:	ChemInform. 20
ISSN:	0931-7597
DOI:	10.1002/chin.198910349
Popis:	The phenylacetyloxymethylene group serves to protect the carboxyl group of benzylpenicillin sulphoxide (2a) during the transformation into 7-ADCA and 7β-amino-3-methoxyceph-3-em-4-carboxylic acid (9), being removed together with the 7-phenylacetyl side chain by means of immobilized penicillin acylase in a single step.
Databáze:	OpenAIRE
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