Acquired haemophilia complicating the remission of a patient with high grade non-Hodgkin's lymphoma treated by fludarabine
Autor: | M.J. Galloway, P.J. Hamilton, C.W. Tiplady |
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Rok vydání: | 2000 |
Předmět: |
Oncology
medicine.medical_specialty business.industry medicine.drug_class Autoantibody Hematology medicine.disease medicine.disease_cause Antimetabolite Fludarabine Lymphoma Non-Hodgkin's lymphoma Autoimmunity medicine.anatomical_structure hemic and lymphatic diseases Internal medicine Immunology Medicine business Complication B cell medicine.drug |
Zdroj: | Clinical & Laboratory Haematology. 22:163-165 |
ISSN: | 0141-9854 |
DOI: | 10.1046/j.1365-2257.2000.00308.x |
Popis: | We report the development of a high titre antibody to factor VIII in a patient with previous high grade B cell non-Hodgkin's lymphoma treated with fludarabine. Unlike previous reports of factor VIII inhibitors and lymphoproliferative disease this patient's lymphoma was in remission. We speculate that the occurrence of the inhibitor is another manifestation of the increasingly recognized autoimmune side-effects of fludarabine. |
Databáze: | OpenAIRE |
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